HDAC inhibitors modulate Hippo pathway signaling in hormone positive breast cancer

Abstract Breast cancer has constantly been the leading causes of death in women, and hormone receptor (HR) positive, HER2 negative is the majority subtype. Histone deacetylase (HDAC) inhibitors (HDACi) have shown clinical benefit in HR ( +) breast cancer patients. The Hippo pathway is an important c...

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Main Authors: Ting-I Lin, Yi-Ru Tseng, Min-Jyun Dong, Chih-Yi Lin, Wei-Ting Chung, Chun-Yu Liu, Yi-Fang Tsai, Chi-Cheng Huang, Ling-Ming Tseng, Ta-Chung Chao, Jiun-I Lai
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Clinical Epigenetics
Online Access:https://doi.org/10.1186/s13148-025-01834-y
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