S100A8/A9 high-expression macrophages mediate renal tubular epithelial cell damage in acute kidney injury following acute type A aortic dissection surgery

S100A8/A9 high-expression macrophages mediate renal tubular epithelial cell damage in acute kidney injury following acute type A aortic dissection surgery

BackgroundAcute kidney injury (AKI) is a major complication after acute type A aortic dissection (ATAAD), with an incidence rate of 20–66.7%. Many patients with AKI after ATAAD surgery show no clear signs of ischemia-reperfusion injury. In our previous study, S100A8 and S100A9 were identified as pre...

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Bibliographic Details
Main Authors: Xiujuan Cai, Xin Li, Jian Shi, Lu Tang, Jie Yang, Ronghuang Yu, Zhigang Wang, Dongjin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
S100A8/A9
aortic dissection
acute kidney injury
macrophage
TNF pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1530741/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2025.1530741/full

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