Polymerized-Type I Collagen Induces Upregulation of Foxp3-Expressing CD4 Regulatory T Cells and Downregulation of IL-17-Producing CD4+ T Cells (Th17) Cells in Collagen-Induced Arthritis

Polymerized-Type I Collagen Induces Upregulation of Foxp3-Expressing CD4 Regulatory T Cells and Downregulation of IL-17-Producing CD4+ T Cells (Th17) Cells in Collagen-Induced Arthritis

Previous studies showed that polymerized-type I collagen (polymerized collagen) exhibits potent immunoregulatory properties. This work evaluated the effect of intramuscular administration of polymerized collagen in early and established collagen-induced arthritis (CIA) in mice and analyzed changes i...

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Main Authors: Janette Furuzawa-Carballeda, Perla Macip-Rodríguez, Angeles S. Galindo-Feria, David Cruz-Robles, Virgina Soto-Abraham, Sergio Escobar-Hernández, Diana Aguilar, Deshiré Alpizar-Rodríguez, Karen Férez-Blando, Luis Llorente
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/618608
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http://dx.doi.org/10.1155/2012/618608

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