Exploring the clinical implications of novel SRD5A2 variants in 46,XY disorders of sex development

This study was conducted retrospectively on a cohort of 68 patients with steroid 5 α-reductase 2 (SRD5A2) deficiency and 46,XY disorders of sex development (DSD). Whole-exon sequencing revealed 28 variants of SRD5A2, and further analysis identified seven novel mutants. The preponderance of variants...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu Mao, Jian-Mei Huang, Yu-Wei Chen-Zhang, He Lin, Yu-Huan Zhang, Ji-Yang Jiang, Xue-Mei Wu, Ling Liao, Yun-Man Tang, Ji-Yun Yang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Asian Journal of Andrology
Subjects:
Online Access:https://journals.lww.com/10.4103/aja202469
Tags: Add Tag
No Tags, Be the first to tag this record!