Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro.

Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro.

Pregnancy is associated with increased β-cell proliferation driven by prolactin. Long noncoding RNAs (lncRNA) are the most abundant RNA species in the mammalian genome, yet, their functional importance is mainly elusive.<h4>Aims/hypothesis</h4>This study tests the hypothesis that lncRNAs...

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Main Authors: Giorgia Sisino, Alex-Xianghua Zhou, Niklas Dahr, Alan Sabirsh, Mangala M Soundarapandian, Ranjan Perera, Erik Larsson-Lekholm, Maria Chiara Magnone, Magnus Althage, Björn Tyrberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182371&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182371&type=printable

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