Rethinking Short-Chain Fatty Acids: A Closer Look at Propionate in Inflammation, Metabolism, and Mucosal Homeostasis

Propionate is a short-chain fatty acid (SCFA) produced by gut microbiota through the fermentation of dietary fibers. Among the SCFAs, butyrate stands out and has been extensively studied for its beneficial effects; however, propionate has received less attention despite its relevant roles in immune...

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Bibliographic Details
Main Authors: Sonia Facchin, Matteo Calgaro, Edoardo V. Savarino
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/15/1130
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