A plant secretory sequence enhances immunogenicity of electroporated COVID-19 DNA vaccines

A plant secretory sequence enhances immunogenicity of electroporated COVID-19 DNA vaccines

IntroductionAs paradigmatically shown by SARS-CoV-2 vaccines, nucleic acids-based vaccines represent powerful tools to rapidly tackle fast emerging pathogens limiting their spread in human populations and/or reducing the health impact in affected patients. Compared with RNA vaccines, DNA vaccines of...

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Bibliographic Details
Main Authors: Olivia Costantina Demurtas, Flavia Novelli, Doriana Triggiani, Caterina Merla, Emanuela Pasquali, Silvia Massa, Rosella Franconi, Claudio Pioli
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medical Technology
Subjects:
DNA vaccines
plant secretory sequence
electro-gene transfer (EGT)
COVID-19
SARS-CoV-2
receptor-binding domain (RBD)
Online Access:https://www.frontiersin.org/articles/10.3389/fmedt.2025.1597179/full
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https://www.frontiersin.org/articles/10.3389/fmedt.2025.1597179/full

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