Long noncoding RNA hottip maintained skeletal homeostasis via suppressing the enhancer of zeste homolog 2 (Ezh2)/histone methylation regulatory axis

Long noncoding RNA hottip maintained skeletal homeostasis via suppressing the enhancer of zeste homolog 2 (Ezh2)/histone methylation regulatory axis

Objective: Recent evidence underscores the pivotal role of long noncoding RNAs (lncRNAs) in orchestrating bone remodeling and skeletal homeostasis by harmonizing osteoblast and osteoclast development. Notably, the oncogenic lncRNA, Hottip, implicated in osteogenesis regulation, remains insufficientl...

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Bibliographic Details
Main Authors: Zhi-Peng Li, Yong-Xin Mai, Shu-Ting Zhou, Chuan-jian Shi, Jiang Shao, Pu-ping Liang, Wei-cheng Liang, Jin-fang Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Non-coding RNA Research
Subjects:
lncRNA hottip
Metabolomics
Skeletal homeostasis
Osteoblast
Osteoclast
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054025000150
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http://www.sciencedirect.com/science/article/pii/S2468054025000150

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