miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma

miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma

Abstract Background Malignant mesothelioma (MM) is a rare and aggressive form of cancer that affects the mesothelial surfaces, associated with exposure to asbestos fibres. To date, no cure is available for MM and therapeutically approved treatments are based on the use of platinum compounds often us...

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Main Authors: Miriam Piccioni, Francesco Di Meo, Anna Valentino, Virginia Campani, Maddalena Arigoni, Mirella Tanori, Mariateresa Mancuso, Rossana Cuciniello, Marco Tomasetti, Federica Monaco, Gaia Goteri, Enrico P. Spugnini, Raffaele A. Calogero, Giuseppe De Rosa, Gianfranco Peluso, Alfonso Baldi, Stefania Crispi
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Mesothelioma
miRNA-503 inhibition
Apoptosis
LNPs
Tumor growth inhibition
Online Access:https://doi.org/10.1186/s13046-025-03283-0
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https://doi.org/10.1186/s13046-025-03283-0

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