Cellular Immunogenicity of Novel Gene Immunogens in Mice Monitored by in Vivo Imaging

Cellular Immunogenicity of Novel Gene Immunogens in Mice Monitored by in Vivo Imaging

The efficient cell-mediated immune response clears cells expressing deoxyribonucleic acid (DNA) immunogens, but there are no methods to monitor this in vivo. We hypothesized that immune-mediated clearance can be monitored in vivo if DNA immunogens are coexpressed with reporter(s). To test this, we d...

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Main Authors: Elizaveta Starodubova, Olga Krotova, David Hallengärd, Yulia Kuzmenko, Gunnel Engström, Diana Legzdina, Oleg Latyshev, Olesja Eliseeva, Anna Karin Maltais, Vera Tunitskaya, Vadim Karpov, Andreas Bråve, Maria Isaguliants
Format: Article
Language:English
Published: SAGE Publishing 2012-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2012.00011
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https://doi.org/10.2310/7290.2012.00011

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