Platelet–Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease

Platelet–Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease

Abstract Kawasaki disease (KD) is a severe acute febrile illness and systemic vasculitis that causes coronary artery aneurysms in young children. Platelet hyperreactivity and an aberrant immune response are key indicators of KD; however, the mechanism by which hyperactive platelets contribute to inf...

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Main Authors: Yuan Zhang, Cuiping Jia, Manli Guo, Qian Chen, Ying Wen, Ting Wang, Yinyin Xie, Xuejiao Fan, Jingwen Gao, Timur O. Yarovinsky, Renjing Liu, Zhiyong Jiang, Mengmeng Wang, Jin Zhou, Di Che, Lanyan Fu, Richard Edelson, Xiaoqiong Gu, John Hwa, Wai Ho Tang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
inflammation
Kawasaki disease
monocyte
platelet
vasculopathy
Online Access:https://doi.org/10.1002/advs.202406282
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https://doi.org/10.1002/advs.202406282

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