Mitophagy’s impacts on cancer and neurodegenerative diseases: implications for future therapies

Mitophagy’s impacts on cancer and neurodegenerative diseases: implications for future therapies

Abstract Substantial evidence supports an inverse relationship between cancer and neurodegenerative diseases (NDDs), but few studies investigate the biological mechanisms underlying this phenomenon. While previous explanations—such as inflammation, reactive oxygen species (ROS), genetic mutations, a...

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Bibliographic Details
Main Authors: Jason Huang, Vincent Truong Pham, Shaozi Fu, Gang Huang, Ya-Guang Liu, Lei Zheng
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Hematology & Oncology
Subjects:
Mitophagy
Mitochondrial dysfunction
Cancer
Neurodegenerative diseases
Inflammation
ROS
Online Access:https://doi.org/10.1186/s13045-025-01727-w
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https://doi.org/10.1186/s13045-025-01727-w

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