RBM47 functions as an anti-oncogene by regulating expression and alternative splicing of cell proliferation and apoptosis associated genes in colorectal cancer cells

RBM47 functions as an anti-oncogene by regulating expression and alternative splicing of cell proliferation and apoptosis associated genes in colorectal cancer cells

Abstract Transcriptional and post-transcriptional regulation mediated by RNA binding proteins (RBPs) have essential influence on the progression of colorectal cancer (CRC), while the underlying mechanisms need to be clarified. In this study, we focused on RBP-RBM47 and overexpressed its expression i...

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Bibliographic Details
Main Authors: Guangshi Liu, Tao Li, Peng Li, Suyan Wei, Kamuran Abulizi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
RBM47
CRC
Alternative splicing
RNA-seq
Anti-tumor
Online Access:https://doi.org/10.1038/s41598-025-05151-5
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https://doi.org/10.1038/s41598-025-05151-5

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