Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study.

Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study.

<h4>Background</h4>Chemoradiotherapy (CRT) has improved organ preservation or overall survival (OS) of locoregionally advanced head and neck squamous cell cancer (LAHNSCC), but in clinical trials of conventional CRT, increasing CRT intensity has not been shown to improve OS. In the Adjuv...

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Main Authors: Akira Kubota, Eiji Nakatani, Kiyoaki Tsukahara, Yasuhisa Hasegawa, Hideki Takemura, Tomonori Terada, Takahide Taguchi, Kunihiko Nagahara, Hiroaki Nakatani, Kunitoshi Yoshino, Yuichiro Higaki, Shigemichi Iwae, Takeshi Beppu, Yutaka Hanamure, Kichinobu Tomita, Naoyuki Kohno, Kazuyoshi Kawabata, Satoshi Teramukai, Masato Fujii, ACTS-HNC Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198391/1/pone.0198391.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210219%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210219T152556Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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