WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancer

WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancer

Abstract Chemoresistance continues to pose a significant challenge in managing colorectal cancer (CRC), resulting in unfavorable outcomes for patients. Recent findings indicate that ferroptosis, an innovative type of regulated cell death, might influence chemoresistance. In this research, we explore...

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Main Authors: Yang Wang, Dachuan Qi, Guijie Ge, Ning Cao, Xiangdong Liu, Na Zhu, Feng Li, Xiang Huang, Kui Yu, Jinzhou Zheng, Daoheng Wang, Wenyan Yao, Lili Chen, Ziyang Dong
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Medicine
Subjects:
Colorectal cancer
Mitochondrial function
Chemoresistance
Ferroptosis
Online Access:https://doi.org/10.1186/s10020-025-01151-3
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https://doi.org/10.1186/s10020-025-01151-3

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