OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response

OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response

Abstract Carbapenem‐resistant Acinetobacter baumannii (CRAB) has become a major threat in the treatment of bacterial infection, and immunotherapy in a non‐antibiotic‐dependent manner is an effective way to overcome CRAB infection. However, the role of the innate immune response in CRAB infection is...

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Bibliographic Details
Main Authors: Yang Yang, Yuanyuan Zeng, Jianjie Zhu, Jianjun Li, Lei Gu, Lin Wei, Zeyi Liu, Jian‐an Huang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
Acinetobacter baumannii
carbapenem‐resistant
cGAS‐STING
mitochondrial DNA
outer membrane protein 38
Online Access:https://doi.org/10.1002/advs.202408292
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https://doi.org/10.1002/advs.202408292

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