Integrated multi-omics analysis and experimental investigation of mitochondrial dynamics-related genes: molecular subtypes, immune landscape, and prognostic implications in lung adenocarcinoma

Integrated multi-omics analysis and experimental investigation of mitochondrial dynamics-related genes: molecular subtypes, immune landscape, and prognostic implications in lung adenocarcinoma

BackgroundLung adenocarcinoma (LUAD) is a common and aggressive subtype of lung cancer associated with poor clinical outcomes. The role of mitochondrial dynamics (MD)-related genes in tumor progression and immune regulation remains poorly understood.MethodsData from public databases were integrated,...

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Bibliographic Details
Main Authors: Sixuan Wu, Junfan Pan, Lijun Zeng, Qihong Pan, Yao Yu, Jincan Lin, Jing Zhang, Yiling Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
LUAD
mitochondrial dynamics
prognostic model
tumor microenvironment
MTCH2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585505/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585505/full

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