Risk factors and outcomes of thyroid immune-related adverse events following PD-1/PD-L1 inhibitors treatment in a large tertiary Chinese center

Risk factors and outcomes of thyroid immune-related adverse events following PD-1/PD-L1 inhibitors treatment in a large tertiary Chinese center

Abstract Objective To investigate the clinical characteristics, related risk factors and outcomes of thyroid immune-related adverse events (irAEs) in patients with malignant solid tumor treated with programmed cell death-1 (PD-1) or programmed cell death-ligand 1 (PD-L1) inhibitors in a large tertia...

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Bibliographic Details
Main Authors: Wenwen Gong, Erhan Zheng, Minchao Liu, Yaliang Han, Zhaohui Lyu, Qinghua Guo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Endocrine Disorders
Subjects:
Thyroid irAEs
Risk factors
Malignant solid tumor
PD-1/PD-L1 inhibitors
Hypothyroidism
Overall survival
Online Access:https://doi.org/10.1186/s12902-025-01986-1
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https://doi.org/10.1186/s12902-025-01986-1

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