BsmI polymorphism in the vitamin D receptor gene is associated with 25-hydroxy vitamin D levels in individuals with cognitive decline

BsmI polymorphism in the vitamin D receptor gene is associated with 25-hydroxy vitamin D levels in individuals with cognitive decline

ABSTRACT Elderly people are at a high risk of developing vitamin D (VitD) deficiency due to both decreased intake and cutaneous synthesis. Most of the biological actions of VitD are mediated by the vitamin D receptor (VDR), which is present in neurons and glial cells of the hippocampus, and in the c...

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Main Authors: Ana Carolina R. de Oliveira, Carolina A. Magalhães, Cristina M. G. Loures, Vanessa G. Fraga, Leonardo C. de Souza, Henrique C. Guimarães, Marco T. G. Cintra, Maria A. Bicalho, Maira C. R. Sousa, Josianne N. Silveira, Ieda F. O. Silva, Paulo Caramelli, Maria G. Carvalho, Karina B. Gomes
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Doença de Alzheimer
disfunção cognitiva
vitamina D
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001100760&lng=en&tlng=en
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001100760&lng=en&tlng=en

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