CRP Stimulates GDF15 Expression in Endothelial Cells through p53

Growth differentiation factor 15 (GDF15) is a multifunctional, secreted protein that is a direct target gene of p53. GDF15 is a prospective biomarker of cardiovascular disease (CVD). C-reactive protein (CRP), like GDF15, is implicated in inflammation and an independent biomarker of CVD. However, the...

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Bibliographic Details
Main Authors: Yoonseo Kim, Nicole Noren Hooten, Michele K. Evans
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/8278039
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