Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

Cerebral ischemia-reperfusion injury (CIRI) is a critical pathological process driving neurological deterioration following ischemic stroke, involving multifaceted mechanisms such as inflammatory cascades, oxidative stress, and programmed cell death (PCD). Deubiquitinases (DUBs), as key regulators o...

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Bibliographic Details
Main Authors: XiaoHong Qin, JiangRui Zhu, HaoRan Lu, MaoRui Yi, ZiLong Zhao, WenFei Zhang, Jing Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
cerebral ischemia-reperfusion injury (CIRI)
deubiquitinases (DUBs)
ischemic stroke
neuroinflammation
oxidative stress
programmed cell death (PCD)
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1588920/full
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https://www.frontiersin.org/articles/10.3389/fnagi.2025.1588920/full

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