Expanding the Role of Heparin Derivatives in Oncology: From Anticoagulation to Antitumor Activity

Expanding the Role of Heparin Derivatives in Oncology: From Anticoagulation to Antitumor Activity

Current research demonstrates the expanding therapeutic potential of heparin derivatives in oncology, extending beyond traditional anticoagulation mechanisms. This systematic analysis examines the structural characteristics, molecular mechanisms, and therapeutic applications of heparin-based compoun...

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Bibliographic Details
Main Authors: Jasmine Holail, Hatouf Husni Sukkarieh, Ahmad Aljada
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
heparin derivatives
low-molecular-weight heparins (LMWHs)
non-anticoagulant heparins (NAC heparins)
cancer therapy
antitumor activity
heparanase inhibition
Online Access:https://www.mdpi.com/1424-8247/18/3/396
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