Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer

Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer

Abstract The global dissemination of mobile colistin resistance (mcr) genes represents a significant public health threat due to colistin’s critical role in treating multidrug-resistant (MDR) bacterial infections. We identified high rates of carbapenem resistance in Escherichia coli (27.82%) and Kle...

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Main Authors: Sirirat Luk-In, Kamonrat Phopin, Sasina Bangmuangngam, Tanittha Chatsuwan, Dhammika Leshan Wannigama, Aye Mya Sithu Shein, Rongpong Plongla, Ratana Lawung, Sakda Yainoy, Warawan Eiamphungporn, Chawalit Chatupheeraphat, Tanawut Tantimongcolwat
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Escherichia coli
Klebsiella pneumoniae
Plasmids
Colistin
Benzyl isothiocyanate
Thailand
Online Access:https://doi.org/10.1038/s41598-025-97424-2
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https://doi.org/10.1038/s41598-025-97424-2

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