B7–H3 and c-MET in advanced prostate cancer: exploring possibilities of novel bi-specific drug development

B7–H3 and c-MET in advanced prostate cancer: exploring possibilities of novel bi-specific drug development

Abstract Purpose Prostate cancer (PCa) is a serious malignancy worldwide with the fifth highest mortality rate among tumors in males, and there are unmet clinical needs for PCa treatment. In this work, we aim to explore the expression and overlap between B7 Homolog 3 protein (B7–H3) and cell-surface...

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Main Authors: Weiying He, Huiyu Li, Wenjia Sun, Yanggeling Zhang, De Wu, Chunxia Ao, Jincheng Wang, Yanan Yang, Xuexue Xiao, Luyao Zhang, Junqiu Yue, Xiyuan Wang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:European Journal of Medical Research
Subjects:
B7–H3
C-MET
Prostate cancer
ADT
Online Access:https://doi.org/10.1186/s40001-025-02729-7
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https://doi.org/10.1186/s40001-025-02729-7

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