Effectiveness, safety, and practicality of intramuscular progesterone in restoring pregnancy outcomes during frozen embryo transfers

Effectiveness, safety, and practicality of intramuscular progesterone in restoring pregnancy outcomes during frozen embryo transfers

ObjectiveTo evaluate whether progesterone (P4) supplementation in patients with low serum progesterone levels after normal luteal phase support (LPS) improves pregnancy outcomes in women undergoing frozen embryo transfer (FET).MethodsA retrospective, single-center cohort study including 1301 vitrifi...

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Main Authors: Chien Ngoc Nguyen, Trang Thi Nhu Nguyen, Thanh Thien Le, Phuong Bich Vu, Lan Thi Phuong Le, Nha Ba Pham, Huong Minh To, Xuyen Thi Nguyen, Ly Thi Tam Nguyen, Van Thi Cam Nguyen, Yen Thi Kim Pham, Tran Hue Tran, Quynh Thi Nguyen, Yen Hoang Nguyen, Tho Thi Vu, Thuy Thi Thu Nguyen, Xuan-Hung Nguyen, Robert J. Norman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
frozen embryo transfer
hormone replacement treatment
luteal phase support
serum progesterone levels
progesterone administration
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1592956/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1592956/full

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