Valency-affinity mapping of multivalent liposomes for tunable target cell discrimination

Multivalency can drive high-avidity binding of ligand-functionalized nanoparticles to cells with high target receptor expression, but it can also contribute to off-target binding to low-expression non-target cells. We explored how ligand affinity and liposome valency shape the resulting binding perf...

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Bibliographic Details
Main Authors: Victor A. Garcia, Paulina M. Eberts, Brenda M. Ogle, Casim A. Sarkar
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Drug Delivery
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2025.2512950
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