Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples

Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples

Prion disease is an infectious and fatal neurodegenerative disease. Western blotting (WB)-based identification of proteinase K (PK)-resistant prion protein (PrPres) is considered a definitive diagnosis of prion diseases. In this study, we aimed to detect PrPres using formalin-fixed paraffin-embedded...

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Bibliographic Details
Main Authors: Sachiko Koyama, Kaoru Yagita, Hideomi Hamasaki, Hideko Noguchi, Masahiro Shijo, Kosuke Matsuzono, Kei-Ichiro Takase, Keita Kai, Shin-Ichi Aishima, Kyoko Itoh, Toshiharu Ninomiya, Naokazu Sasagasako, Hiroyuki Honda
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Prion
Subjects:
FFPE
PK-resistant prion protein
Prion disease
Sporadic Creutzfeldt–Jakob disease
western blotting
Online Access:https://www.tandfonline.com/doi/10.1080/19336896.2024.2337981
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