Analysis of Colorectal Cancer Gene Mutations and Application of Long Blocker Displacement Amplification Technology for High-Throughput Mutation Detection

Analysis of Colorectal Cancer Gene Mutations and Application of Long Blocker Displacement Amplification Technology for High-Throughput Mutation Detection

Genetic mutation detection for colorectal cancer (CRC) is crucial for precision diagnosis and treatment, yet current methods often suffer from challenges such as low sensitivity, time consumption, and high costs. In our preliminary bioinformatic analysis of 751 CRC cases from The Cancer Genome Atlas...

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Bibliographic Details
Main Authors: Ping Lu, Xinglei Su, Sirui Leong, Xuehao Xiu, Ping Song, Junjie Peng, Yunpei Si
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biosensors
Subjects:
colorectal cancer
KRAS mutation
LBDA technology
rapid detection
bioinformatics
Online Access:https://www.mdpi.com/2079-6374/15/5/308
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