A systematic review of the neuroprotective role and biomarker potential of GDF15 in neurodegeneration

A systematic review of the neuroprotective role and biomarker potential of GDF15 in neurodegeneration

Neurodegeneration is characteristically multifaceted, with limited therapeutic options. One of the chief pathophysiological mechanisms driving these conditions is neuroinflammation, prompting increasing clinical interest in immunomodulatory agents. Growth differentiation factor 15 (GDF15; previously...

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Bibliographic Details
Main Authors: Finula I. Isik, Shannon Thomson, John F. Cueto, Jessica Spathos, Samuel N. Breit, Vicky W. W. Tsai, David A. Brown, Caitlin A. Finney
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
GDF15
GFRAL
neurodegeneration
neurotrauma
inflammation
neurotrophic
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1514518/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1514518/full

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