Impact of a preceding radiotherapy on the outcome of immune checkpoint inhibition in metastatic melanoma: a multicenter retrospective cohort study of the DeCOG

Impact of a preceding radiotherapy on the outcome of immune checkpoint inhibition in metastatic melanoma: a multicenter retrospective cohort study of the DeCOG

Background Immune checkpoint inhibition (ICI) is an essential treatment option in melanoma. Its outcome may be improved by a preceding radiation of metastases. This study aimed to investigate the impact of a preceding radiotherapy on the clinical outcome of ICI treatment.Methods This multicenter ret...

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Main Authors: Dirk Schadendorf, Carola Berking, Lucie Heinzerling, Lisa Zimmer, Ralf Gutzmer, Alexander Kreuter, Andreas Stang, Elisabeth Livingstone, Benjamin Weide, Eleftheria Chorti, Selma Ugurel, Anja Gesierich, Jürgen C Becker, Peter Mohr, Max Schlaak, Patrick Terheyden, Janine Gronewold, Rudolf Herbst, Carmen Loquai, Sarah Knispel, Hildegard Lax, Carsten Weishaupt, Claudia Pföhler, Katharina C Kaehler, Jochen Utikal, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal
Format: Article
Language:English
Published: BMJ Publishing Group 2020-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000395.full
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