Synthesis of Indole Derivatives via Aryl Triazole Ring-Opening and Subsequent Cyclization

A metal-free two-step synthetic approach for obtaining indole derivatives from aryl triazole fragment-containing compounds has been developed. In the first step, the Dimroth equilibrium, followed by nitrogen extrusion, Wolff rearrangement, and amine nucleophile addition, leads to the formation of &l...

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Bibliographic Details
Main Authors: Aleksejs Burcevs, Armands Sebris, Irina Novosjolova, Anatoly Mishnev, Māris Turks
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/2/337
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