Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport
Percutaneous pancreatic core biopsy is conclusive but challenging due to large-diameter needles, while smaller-diameter needles used in aspiration methods suffer from buckling and clogging. Inspired by the ovipositor of parasitic wasps, which resists buckling through self-propulsion and prevents clo...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1497221/full |
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| author | Jette Bloemberg Suzanne van Wees Suzanne van Wees Vera G. Kortman Aimée Sakes |
| author_facet | Jette Bloemberg Suzanne van Wees Suzanne van Wees Vera G. Kortman Aimée Sakes |
| author_sort | Jette Bloemberg |
| collection | DOAJ |
| description | Percutaneous pancreatic core biopsy is conclusive but challenging due to large-diameter needles, while smaller-diameter needles used in aspiration methods suffer from buckling and clogging. Inspired by the ovipositor of parasitic wasps, which resists buckling through self-propulsion and prevents clogging via friction-based transport, research has led to the integration of these functionalities into multi-segment needle designs or tissue transport system designs. This study aimed to combine these wasp-inspired functionalities into a single biopsy needle by changing the interconnection of the needle segments. The resulting biopsy needle features six parallel needle segments interconnected by a ring passing through slots along the length of the needle segments, enabling a wasp-inspired reciprocating motion. Actuation employs a cam and follower mechanism for controlled translation of the segments. The needle prototype, constructed from nitinol rods and stainless steel rings, measures 3 mm in outer diameter and 1 mm in inner diameter. Testing in gelatin phantoms demonstrated efficient gelatin core transport (up to 69.9% ± 9.1% transport efficiency) and self-propulsion (0.842 ± 0.042 slip ratio). Future iterations should aim to reduce the outer diameter while maintaining tissue yield. The design offers a promising new avenue for wasp-inspired medical tools, potentially enhancing early pancreatic cancer detection, thus reducing healthcare costs and patient complications. |
| format | Article |
| id | doaj-art-88343d91bdd2475ebdd6117c4c5433b4 |
| institution | Kabale University |
| issn | 2296-4185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj-art-88343d91bdd2475ebdd6117c4c5433b42025-01-06T05:13:11ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-01-011210.3389/fbioe.2024.14972211497221Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transportJette Bloemberg0Suzanne van Wees1Suzanne van Wees2Vera G. Kortman3Aimée Sakes4Department of BioMechanical Engineering, Bio-Inspired Technology Group, Faculty of Mechanical Engineering, Delft University of Technology, Delft, NetherlandsDepartment of BioMechanical Engineering, Bio-Inspired Technology Group, Faculty of Mechanical Engineering, Delft University of Technology, Delft, NetherlandsDepartment of Biomedical Engineering, Faculty of Science and Engineering, University of Groningen, Groningen, NetherlandsDepartment of BioMechanical Engineering, Bio-Inspired Technology Group, Faculty of Mechanical Engineering, Delft University of Technology, Delft, NetherlandsDepartment of BioMechanical Engineering, Bio-Inspired Technology Group, Faculty of Mechanical Engineering, Delft University of Technology, Delft, NetherlandsPercutaneous pancreatic core biopsy is conclusive but challenging due to large-diameter needles, while smaller-diameter needles used in aspiration methods suffer from buckling and clogging. Inspired by the ovipositor of parasitic wasps, which resists buckling through self-propulsion and prevents clogging via friction-based transport, research has led to the integration of these functionalities into multi-segment needle designs or tissue transport system designs. This study aimed to combine these wasp-inspired functionalities into a single biopsy needle by changing the interconnection of the needle segments. The resulting biopsy needle features six parallel needle segments interconnected by a ring passing through slots along the length of the needle segments, enabling a wasp-inspired reciprocating motion. Actuation employs a cam and follower mechanism for controlled translation of the segments. The needle prototype, constructed from nitinol rods and stainless steel rings, measures 3 mm in outer diameter and 1 mm in inner diameter. Testing in gelatin phantoms demonstrated efficient gelatin core transport (up to 69.9% ± 9.1% transport efficiency) and self-propulsion (0.842 ± 0.042 slip ratio). Future iterations should aim to reduce the outer diameter while maintaining tissue yield. The design offers a promising new avenue for wasp-inspired medical tools, potentially enhancing early pancreatic cancer detection, thus reducing healthcare costs and patient complications.https://www.frontiersin.org/articles/10.3389/fbioe.2024.1497221/fullbio-inspired designbiomimeticsmedical device designminimally invasive surgeryovipositorpancreatic biopsy |
| spellingShingle | Jette Bloemberg Suzanne van Wees Suzanne van Wees Vera G. Kortman Aimée Sakes Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport Frontiers in Bioengineering and Biotechnology bio-inspired design biomimetics medical device design minimally invasive surgery ovipositor pancreatic biopsy |
| title | Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport |
| title_full | Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport |
| title_fullStr | Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport |
| title_full_unstemmed | Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport |
| title_short | Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport |
| title_sort | design of a wasp inspired biopsy needle capable of self propulsion and friction based tissue transport |
| topic | bio-inspired design biomimetics medical device design minimally invasive surgery ovipositor pancreatic biopsy |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1497221/full |
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