Prediction of drug exposure in hepatic impairment: a comparison between minimal physiologically based pharmacokinetic (mPBPK) and whole body PBPK models
Aim: The objective of this study was to develop a minimal physiologically based pharmacokinetic (mPBPK) model to predict area under the curve (AUC) and maximum plasma concentration (Cmax) of drugs in subjects with varying degrees of hepatic impairment and compare this mPBPK model with the whole body...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Open Exploration
2025-02-01
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| Series: | Exploration of Drug Science |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/uploads/Article/A100894/100894.pdf |
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