Induction of type 2 and 3 deiodinase in the blood cells of critically ill patients

Induction of type 2 and 3 deiodinase in the blood cells of critically ill patients

Altered type 2 and 3 deiodinase (D2 and D3) can disrupt thyroid hormone metabolism and contribute to non-thyroidal illness syndrome (NTIS). The impact of the colocalization of D2 and D3, and their expression in immune cells isolated from critically ill patients, are still not fully understood. Our o...

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Main Authors: Thaliane Carvalho Oliveira, André Cardoso Braun, Rachel Pinto Dornelles Dutra, Mariana Marchesan Moreira Breit, Julia Brum Abib, Ludmilla C D Thomazini, Gustavo Argenti, Maria Paula Alves Correa, Giovanna Almeida, Josi Vidart, Simone Magagnin Wajner
Format: Article
Language:English
Published: Bioscientifica 2025-03-01
Series:Endocrine Connections
Subjects:
thyroid hormone
type 3 deiodinase
oxidative stress
immune cells
Online Access:https://ec.bioscientifica.com/view/journals/ec/14/4/EC-24-0677.xml
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