Pyrimidinetrione benzodioxol ameliorates MAFLD-induced liver tumorigenesis and mood disorders in mice

Abstract The Western diets (WD) induced metabolic dysfunction-associated fatty liver disease (MAFLD) has become a major clinical burden. No pharmacological agent has been approved to treat MAFLD-induced liver cancer and systemic symptoms. In this study, mice were fed a WD combined with a CCl4 inject...

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Bibliographic Details
Main Authors: Fang-Yu Hsu, Wan-Chun Chiu, Fat-Moon Suk, Chun-Ya Lee, Ming-Hua Hsu, Yi-Jen Liao
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Gut and Liver
Online Access:https://doi.org/10.1038/s44355-025-00023-1
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