Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat

<b>Aim:</b> Ghrelin, obestatin and leptin hormones are called appetite regulating hormones. It reported that ghrelin initiates feeding, obestatin suppresses appetite and leptin gives a feeling of fullness. In human and other mammalian species, studies have reported that ghrelin, obestati...

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Main Authors: Zelal Karakoç, Uğur Topaloğlu, Muzaffer Aydın Ketani
Format: Article
Language:English
Published: Selcuk University Press
Series:Eurasian Journal of Veterinary Sciences
Subjects:
Online Access:http://eurasianjvetsci.org/pdf.php3?id=1264
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author Zelal Karakoç
Uğur Topaloğlu
Muzaffer Aydın Ketani
author_facet Zelal Karakoç
Uğur Topaloğlu
Muzaffer Aydın Ketani
author_sort Zelal Karakoç
collection DOAJ
description <b>Aim:</b> Ghrelin, obestatin and leptin hormones are called appetite regulating hormones. It reported that ghrelin initiates feeding, obestatin suppresses appetite and leptin gives a feeling of fullness. In human and other mammalian species, studies have reported that ghrelin, obestatin and leptin are expressed at different concentrations from all parts of the stomach. The present study was conducted to determine the expression of ghrelin, obestatin and leptin hormones in hair goat abomasum.<p> <b>Materials and Methods: </b>The abomasum tissues for the study were obtained from 6-8-month-old kids and were collected from cardia, fundus and pylorus regions of the animals abomasums. The ghrelin, obestatin and leptin immunohistochemical staining methods were used, which were applied to all of the sections following the routine histological process.<p> <b>Results:</b> The immunoreactivity of ghrelin, obestatin and leptin was found to be different in all parts of the abomasum. Immunoreactivity was found to be dispersed settlement the abomasum in the cardia region. According to the mean H score, it was determined that ghrelin, obestatin and leptin were intensely expressed in the cardia, pilorus and fundus regions.<p> <b>Conclusion: </b>The appetite hormones (ghrelin, obastatin and leptin) were expressed at different concentrations from the cardia, fundus and pilorus regions in the abomazum, suggesting that these hormones perform similar functions in hair goats considering their physiological effects on feed intake. More research is needed to about use of animal nutrition of ghrelin, obestatin and leptin hormones.
format Article
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institution Kabale University
issn 1309-6958
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language English
publisher Selcuk University Press
record_format Article
series Eurasian Journal of Veterinary Sciences
spelling doaj-art-87da134257e34c7688ff9040abd8c3f52025-01-03T01:36:24ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19533542042091264Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goatZelal KarakoçUğur Topaloğlu0Muzaffer Aydın Ketani1Dicle Üniversitesi Veteriner Fakültesi Histoloji ve Embriyoloji Anabilim Dalı, Diyarbakır, TürkiyeDicle Üniversitesi Veteriner Fakültesi Histoloji ve Embriyoloji Anabilim Dalı, Diyarbakır, Türkiye<b>Aim:</b> Ghrelin, obestatin and leptin hormones are called appetite regulating hormones. It reported that ghrelin initiates feeding, obestatin suppresses appetite and leptin gives a feeling of fullness. In human and other mammalian species, studies have reported that ghrelin, obestatin and leptin are expressed at different concentrations from all parts of the stomach. The present study was conducted to determine the expression of ghrelin, obestatin and leptin hormones in hair goat abomasum.<p> <b>Materials and Methods: </b>The abomasum tissues for the study were obtained from 6-8-month-old kids and were collected from cardia, fundus and pylorus regions of the animals abomasums. The ghrelin, obestatin and leptin immunohistochemical staining methods were used, which were applied to all of the sections following the routine histological process.<p> <b>Results:</b> The immunoreactivity of ghrelin, obestatin and leptin was found to be different in all parts of the abomasum. Immunoreactivity was found to be dispersed settlement the abomasum in the cardia region. According to the mean H score, it was determined that ghrelin, obestatin and leptin were intensely expressed in the cardia, pilorus and fundus regions.<p> <b>Conclusion: </b>The appetite hormones (ghrelin, obastatin and leptin) were expressed at different concentrations from the cardia, fundus and pilorus regions in the abomazum, suggesting that these hormones perform similar functions in hair goats considering their physiological effects on feed intake. More research is needed to about use of animal nutrition of ghrelin, obestatin and leptin hormones.http://eurasianjvetsci.org/pdf.php3?id=1264abomasumappetite hormoneshair goatimmunohis
spellingShingle Zelal Karakoç
Uğur Topaloğlu
Muzaffer Aydın Ketani
Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat
Eurasian Journal of Veterinary Sciences
abomasum
appetite hormones
hair goat
immunohis
title Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat
title_full Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat
title_fullStr Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat
title_full_unstemmed Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat
title_short Immunohistochemical distribution of ghrelin, obestatin and leptin hormones in the abomasum of hair goat
title_sort immunohistochemical distribution of ghrelin obestatin and leptin hormones in the abomasum of hair goat
topic abomasum
appetite hormones
hair goat
immunohis
url http://eurasianjvetsci.org/pdf.php3?id=1264
work_keys_str_mv AT zelalkarakoc immunohistochemicaldistributionofghrelinobestatinandleptinhormonesintheabomasumofhairgoat
AT ugurtopaloglu immunohistochemicaldistributionofghrelinobestatinandleptinhormonesintheabomasumofhairgoat
AT muzafferaydınketani immunohistochemicaldistributionofghrelinobestatinandleptinhormonesintheabomasumofhairgoat