Chemogenetic stimulation of phrenic motor output and diaphragm activity

Impaired respiratory motor output contributes to morbidity and mortality in many neurodegenerative diseases and neurologic injuries. We investigated if expressing designer receptors exclusively activated by designer drugs (DREADDs) in the mid-cervical spinal cord could effectively stimulate phrenic...

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Bibliographic Details
Main Authors: Ethan S Benevides, Prajwal P Thakre, Sabhya Rana, Michael D Sunshine, Victoria N Jensen, Karim Oweiss, David D Fuller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
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Online Access:https://elifesciences.org/articles/97846
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