Methods to Evaluate the Effect of Ethanol on the Folate Analogue: Fluorescein Methotrexate Uptake in Human Proximal Tubular Cells

Ethanol-induced folate deficiency is due to effects of ethanol on folate metabolism and absorption. We have already shown by using different methods that ethanol interferes with reabsorption of folate from the proximal tubule. In this study, we have used the folate analogue, the fluorescein methotre...

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Bibliographic Details
Main Authors: Sivakumar JT Gowder, Kenneth E. McMartin
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2009/291349
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