Plasma anti-PRTN3 IgG and IgM autoantibodies: novel biomarkers for early detection of lung adenocarcinoma

BackgroundProteinase 3 (PRTN3) has been recognized as a crucial target for anti-neutrophil cytoplasmic autoantibody. However, the relationship between anti-PRTN3 autoantibody and cancer remains largely unexplored.MethodsImmunohistochemistry was used to detect the level of PRTN3 in lung adenocarcinom...

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Bibliographic Details
Main Authors: Yutong Li, Linhong Wang, Fengqi Chen, Rulan Liao, Jing Li, Xiaobin Cao, Songyun Ouyang, Liping Dai, Renle Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1534078/full
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