Bedside implications of the use of surrogate endpoints in solid and haematological cancers: implications for our reliance on PFS, DFS, ORR, MRD and more

Clinical endpoints, such as overall survival, directly measure relevant outcomes. Surrogate endpoints, in contrast, are intermediate, stand-in measures of various tumour-related metrics and include tumour growth, tumour shrinkage, blood results, etc. Surrogates may be a time point measurement, that...

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Bibliographic Details
Main Authors: Vinay Prasad, Alyson Haslam, Timothée Olivier, Dagney Ochoa, Eduardo Fernandez
Format: Article
Language:English
Published: BMJ Publishing Group 2024-09-01
Series:BMJ Oncology
Online Access:https://bmjoncology.bmj.com/content/3/1/e000364.full
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