Cross-laboratory replication of pseudomyxoma peritonei tumor microbiome reveals reproducible microbial signatures

Cross-laboratory replication of pseudomyxoma peritonei tumor microbiome reveals reproducible microbial signatures

ABSTRACT Recent work has demonstrated that cancer-specific microbial communities often colonize tumor tissues. However, untangling low-biomass signals from environmental contamination makes this research technically challenging. We utilize pseudomyxoma peritonei (PMP), a cancer characterized by the...

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Main Authors: Victoria F. Nieciecki, Faith C. Blum, Ryan C. Johnson, Traci L. Testerman, Tom J. McAvoy, Mary Caitlin King, Vadim Gushchin, Jeannette M. Whitmire, Kenneth G. Frey, Lindsay Glang, Dessiree Peña-Gomez, Kimberly A. Bishop-Lilly, Armando Sardi, D. Scott Merrell, Jessica L. Metcalf
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mSphere
Subjects:
reproducibility
contamination
amplicon sequencing
source tracking
Pseudomyxoma Peritonei
colorectal cancer
Online Access:https://journals.asm.org/doi/10.1128/msphere.00652-24
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https://journals.asm.org/doi/10.1128/msphere.00652-24

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