Exploring the co‐morbid relationship between Alzheimer's disease and lung cancer in the 5xFAD transgenic mouse model

Exploring the co‐morbid relationship between Alzheimer's disease and lung cancer in the 5xFAD transgenic mouse model

Abstract Background Alzheimer's disease (AD) and lung cancer are leading causes of mortality among the older population. Epidemiological evidence suggests an antagonistic relationship between them, whereby patients with AD exhibit a reduced risk of developing cancer and vice versa. However, the...

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Bibliographic Details
Main Authors: Mingfeng Li, Xinghan Wu, Lin Jiang, Min Liu, Gong Yanju, Xiaomeng Li, Fan Tian, Fan Ye, Jinlong Wang, Siyuan Wang, Chuan Qin, Ling Zhang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Animal Models and Experimental Medicine
Subjects:
Alzheimer's disease
CD8+ T cell
ferroptosis
lung cancer
single‐cell transcriptomics
Online Access:https://doi.org/10.1002/ame2.12527
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https://doi.org/10.1002/ame2.12527

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