Effects of Rho inhibitors on membrane depolarization‐induced contraction of male rat caudal arterial smooth muscle

Abstract We previously reported that depolarization of the vascular smooth muscle plasma membrane activates the Ca2+‐dependent proline‐rich tyrosine kinase 2 (Pyk2) upstream of the RhoA/Rho‐associated kinase (ROCK) pathway, leading to phosphorylation of the myosin‐targeting subunit of myosin light c...

Full description

Saved in:
Bibliographic Details
Main Authors: Kazuki Aida, Reiko Ishii‐Nozawa, Mitsuo Mita
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.70293
Tags: Add Tag
No Tags, Be the first to tag this record!