METTL3 promotes the progression of non-alcoholic fatty liver disease by mediating m6A methylation of FAS

Abstract N6-methyladenosine (m6A) is involved in the development of non-alcoholic fatty liver disease (NAFLD). Here, we aimed to investigate the effect of m6A methyltransferase METTL3 on liver damage in high-fat diet (HFD)-induced mouse model and hepatocyte damage treated with free fatty acid (FFA)....

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Bibliographic Details
Main Authors: Qunhua Li, Junying Xiang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-90419-z
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