IL-1 Receptor Antagonist Anakinra Inhibits the Effect of IL-1β- Mediated Osteoclast Formation by Periodontal Ligament Fibroblasts

IL-1 Receptor Antagonist Anakinra Inhibits the Effect of IL-1β- Mediated Osteoclast Formation by Periodontal Ligament Fibroblasts

Rheumatoid arthritis and periodontitis are comorbidities that share mutual pathways. IL-1β is a pro-inflammatory cytokine that plays a crucial role in both diseases. One of the treatment options for rheumatoid arthritis is the use of an IL-1 receptor antagonist (IL-1RA) such as anakinra. Anakinra te...

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Bibliographic Details
Main Authors: Elizabeth Steemers, Wael M. I. Talbi, Jolanda M. A. Hogervorst, Ton Schoenmaker, Teun J. de Vries
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biology
Subjects:
osteoclast
anakinra
periodontal ligament fibroblast
periodontitis
inflammatory bone disease
Online Access:https://www.mdpi.com/2079-7737/14/3/250
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