Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway

Abstract Background Axon regeneration within the mammalian central nervous system is extremely limited. In optic neuropathy conditions like glaucoma, the inability of retinal ganglion cell (RGC) axons to regenerate is a major impediment to functional recovery. In contrast, adult teleost fish such as...

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Bibliographic Details
Main Authors: Mengming Hu, Matthew B. Veldman
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-025-00807-2
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