A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates

A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates

Adenosine triphosphate-binding cassette (ABC) transporters form a ubiquitous superfamily of integral membrane proteins involved in the translocation of substrates across membranes. Human ABC transporters are closely linked to the pathogenesis of diseases such as cancer, metabolic diseases, and Alzhe...

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Bibliographic Details
Main Authors: Iqra Younus, Robert C. Ford, Stephen M. Prince
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Membranes
Subjects:
ABC transporter
ortholog
<i>Saccharomyces cerevisiae</i>
bioinformatics
membrane protein
Online Access:https://www.mdpi.com/2077-0375/15/1/20
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