Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs

Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs

Abstract This study aimed to investigate the in vitro performance of self-nanoemulsifying drug delivery systems (SNEDDSs) of Ornidazole (ORD), a poorly water-soluble drug. Self-nanoemulsifying drug delivery systems of ORD were prepared using various oils, non-ionic surfactants, and/or water-soluble...

Full description

Saved in:
Bibliographic Details
Main Authors: Popat Mohite, Shruti Sule, Anil Pawar, Hanan M. Alharbi, Swastika Maitra, Vetriselvan Subramaniyan, Vinoth Kumarasamy, Daniel Ejim Uti, Celestine O. Ogbu, Simon Inedu Oodo, Ajoy Kumer, Ayodeji Oluwafemi Idowu, Okechukwu N. N. Okoye
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Ornidazole self-nano emulsifying system
Surfactant
Cosurfactant, solubility
Online Access:https://doi.org/10.1038/s41598-024-73760-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-024-73760-7

Similar Items