Study protocol for a phase II, double-blind, randomised controlled trial of cannabidiol (CBD) compared with placebo for reduction of brain neuroinflammation in adults with chronic low back pain

Introduction Chronic pain is a debilitating medical problem that is difficult to treat. Neuroinflammatory pathways have emerged as a potential therapeutic target, as preclinical studies have demonstrated that glial cells and neuroglial interactions play a role in the establishment and maintenance of...

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Main Authors: Yi Zhang, Robert Edwards, A Eden Evins, Jodi M Gilman, Chelsea K Pike, Minhae Kim, Kristina Schnitzer, Nathaniel Mercaldo, Vitaly Napadow, Erin Janas Morrissey, Zeynab Alshelh, Marco L Loggia
Format: Article
Language:English
Published: BMJ Publishing Group 2022-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/9/e063613.full
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