Safety and efficacy analysis of neoadjuvant radiotherapy combined with concurrent paclitaxel plus nedaplatin versus other platinum-based chemotherapy for thoracic segmental esophageal squamous cell carcinoma

Safety and efficacy analysis of neoadjuvant radiotherapy combined with concurrent paclitaxel plus nedaplatin versus other platinum-based chemotherapy for thoracic segmental esophageal squamous cell carcinoma

BackgroundEsophageal cancer is among the leading causes of cancer-related mortality in males. This study aimed to evaluate the efficacy and safety of nedaplatin (NDP) in comparison to other platinum-based (OPB) agents combined with paclitaxel and concurrent neoadjuvant radiotherapy for locally advan...

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Bibliographic Details
Main Authors: Qingyang Zhuang, Hui Li, Lirui Tang, Hongying Zheng, Jiancheng Li, Junxin Wu, Jinluan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
nedaplatin
platinum
neoadjuvant chemoradiotherapy
esophageal squamous cell carcinoma
safety analysis
efficacy analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1582481/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1582481/full

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